The effects of diabetes mellitus include long-term damage, dysfunction and failure of various organs

About 80% of adults apparently with recently diagnosed Type 2 diabetes but with GAD auto-antibodies (i.e. LADA) progress to insulin requirement within 6 years.

• About 80% of adults apparently with recently diagnosed Type 2 diabetes but with GAD auto-antibodies (i.e. LADA) progress to insulin requirement within 6 years.

• The potential value of identifying this group at high risk of progression to insulin dependence includes:

• the avoidance of using metformin treatment
• the early introduction of insulin therapy

•