Time
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Proposed topics
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Speakers
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Day 1
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Registration
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I. Introductory presentations
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9:00 – 9:45
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Pharmacokinetics and pharmacodynamic concepts
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Tobias Paehler, Sanofi, Germany
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9:45 –10:30
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Computational approaches for prediction/simulation of drug delivery
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Tarek Mounir, Univ Nancy, France
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10:30 – 11:00
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Coffee break
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11:00 – 11:45
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In vitro/in vivo correlation in drug delivery
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Jean-Michel Cardot, (Laboratoire Biopharmacie, Univ Clermont 1, Clermont-Ferrand)
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11:45 – 12:30
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Principles of Electroporation for drug delivery
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Marie-Pierre Rols (Institute of pharmacology and structural biology, Toulouse, France) (A confirmer par Marie-Pierre)
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12:30 – 13:15
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Electroporation : characterization, tools, and constraints for in vivo delivery
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Damijan Miklavcic (Univ Ljubljana, Ljubljana, Slovenia)
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13:15 – 14:30
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Lunch break and Networking
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I. Oral route
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14:30 – 15:15
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Current scenario, barriers, and challenges
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Clive Wilson, Univ Strathclyde, UK
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15:15 – 16:00
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Computational models
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Michael B. Bolger, Simulations Plus, California, USA
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16:00 – 16:30
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Coffee break
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16:30 – 17:15
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In vitro models for assessment of oral drug absorption
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Per Artursson
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Short oral communications
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17 :15 – 17 :30
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PLGA particles as a vector for oral insulin delivery: in vitro and in vivo validation of biofunctionality
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El Hadji Mouhamadou Bamba Diop, University of Strasbourg, France
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17 :30 – 17 :45
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Chitosan nanocapsules for peptide delivery
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Belén L. Bouzo et al., University of Santiago de Compostela, Spain
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17 :45 – 18 :00
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A neurofilament-derived peptide targets neural stem cells
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Joel Eyer, University of Angers, France
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18 :00 – 18 :15
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Improving the ability of S4(13)-PV cell-penetrating peptide to mediate siRNA delivery through peptide acylation
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Catarina M. Morais et al., University of Coimbra, Portugal
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Day 2
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II. Parenteral route
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1. Intravenous (models/tools for drug delivery to cancer and to brain)
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9:00 – 9:45
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Physiological barriers to drug delivery by i.v. route, clinical relevance, and challenges)
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Jean Marie Devoisselle, Univ Montpellier, France
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9:45 – 10:30
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In vitro and in vivo models for drug delivery to cancer
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Khaled Greish, Univ Otago, New Zealand
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10:30 – 11:00
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Coffee break
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|
11:00 – 11:45
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Electroporation in Preclinic :
Electrochemotherapy (ECT) for cutaneous cancers
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Gregor Sersa ((Institute of Oncology Ljubljana, Zaloška cesta 2, SI - 1000 Ljubljana, Slovenia)
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11:45 – 12:30
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Targeting the Blood-brain-Barrier to improve drug delivery to the brain of low molecular drugs
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Xavier Descleves, Univ Paris Descartes
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12 :30 – 13:15
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Targeting the Blood-brain-Barrier to improve drug delivery to the brain of macromolecules
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Didier Betbeder, Lille, France
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13:15 – 14:30
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Lunch break and networking
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2. Alternative routes: Pulmonary & Nasal, Cutaneous
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14:30 – 15:15
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Drug delivery through pulmonary route: Physiology, barriers, and the associated challenges
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Rita Vanbever (Univ Louvain, Belgium)
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15:15 – 16:00
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In vitro and in vivo models for drug delivery to lung
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Carsten Ehrhardt, Univ Dublin, Ireland
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16:00 – 16:30
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Coffee Break
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Short oral communications
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|
16:30 – 16 :45
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Biodistribution, tumor targeting and melanoma anticancer properties of innovative pegylated siRNA lipid nanocapsules
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Pauline Resnier et al., University of Angers, France
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16:45 – 17 :00
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Platform KINE C3 : relevant technological methods to assess brain bioavailability of new therapeutic compounds.
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Thibaud Thiollier et al., Cynbiose SAS, France
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17:00 – 17 :15
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Organized and differentiated 3D model mimicking the human pulmonary alveolar epithelium: an alternative model for drug discovery, toxicology and radiobiology
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Romain Grall et al., CEA, Fontenay-aux-Roses, France
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17:15 – 17 :30
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Pegalation of the metal organic framework, MIL89 improves stability and
confers an inhibitory effect on iNOS activity in macrophages
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Nura A Mohamed et al., Imperial college, United Kingdom
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17:30 – 17 :45
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Development and optimization of pegylated lipoplexes for vaginal application
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Anna Lechanteur et al., University of Liege, Liege, Belgium
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17:45 – 18 :00
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Intrapulmonary delivery of gadolinum-based nanoparticles: a theranostic approach for lung imaging and radiosensitization
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Sandrine Dufort et al. INSERM-UJF U823, Grenoble, France
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Day 3
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9:00 – 9:45
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Drug delivery by cutaneous route: Physiology, barriers, associated challenges, and in vitro/in vivo models
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B. Delgado-Charro, Bath, United Kingdom
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9:45– 10:30
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DNA electroporation for local delivery of therapeutic proteins and vaccines
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Gaelle Vandermeulen (Louvain Drug Research Institute, Univ Catholique de Louvain, Brussels, Belgium)
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10:30 – 11:00
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Coffee break
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11:00 – 11:45
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Current clinical experience on electroporation based treatments, and future prospects
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Julie Gehl (Herlev Hospital/Herlev Ringvej 75/ 2730 Herlev/Copenhagen, Denmark)
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11:45 – 12:30
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Nanomedicine revolution: the path through regulatory science into personalized medicine
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Rogerio Gaspar, Portugal
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12:30
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Lunch & End of the Workshop
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