EFFECT OF PREOPERATIVE INFUSION VOLUME ON FREQUENCY OF INTRAOPERATIVE NAUSEA
AND VOMITING AFTER SPINAL ANAESTHESIA IN PARTURIENT UNDERGONE CAESARIAN
OPERATION (Pilot study)
Shifman E.M.
1
, Filippovich G.V.
2
, Pogodin A.M.
4
, Tikhova G.P.
3
1Russian University of Peoples Friendship,Moscow, Russia; 2Kulakov Scientific Center of Obstetrics,
Gynecology and Perinatology, Moscow, Russia; 3"Severstal’" Maternity Hospital, Cherepovets, Russia;
4IntelTeck Lab Ltd., Petrozavodsk, Russia
correspondence to:
Tikhova G.P.
e-mail:
gala©ritical.ru
Abstract:
Purpose of the study was to define a prophylactic effect of different preload volumes on the rate of
intraoperative nausea and vomiting (IONV) as a complication due to spinal anaesthesia (SA) during
caesarian operation (SO) in parturient. Data for analysis was collected during clinical observational multi-
center research included several medical centers. Statistics involved originally developed method allowed to
analyze relative risk changing along the entire interval of all applied preload volumes. The results suppose
that preload is effective method of IONV prophylactics in parturient during SO under SA if only infused
preload volumes do not break specially determined limits of effective interval. If preload volume value is out
of this range then preinfusion may lead to increasing risk of IONV occurrence.
Key words:
caesarian operation, spinal anaesthesia, intraoperative nausea and vomiting, preload
AN-1401-026
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