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Measure bar should be 150mm at 100% scale 

Customer


Description

Item Code

Profile

Size


Min. Point Size

Market


Language

Proof By


Proof No.

Date


Artwork No.

Pharma


Code

Colours Used

Wockhardt UK Limited

Heparin Flush Soln 10U/ML Amp

106935-2

n/a


375mm x 148mm

matthew.turrell

1

24/09/2015



597013

322


Process Black

Text free area (non-printing)

Pharmacode Area (non-printing)

Keylines (non printing)

artwork.leicester@multipkg.com

Clearly mark any amendments on one proof and return to MPS

Warning! 

We cannot accept responsibility for any errors 

in this proof after approval. Whilst we take extreme care 

at all times to ensure accuracy to our clientʼs brief,

the final responsibility must be taken by our client. 

IF YOU SIGN THIS PROOF YOU ARE SIGNIFYING

FULL APPROVAL OF DESIGN AND TEXT.

UK

English



8.5pt (main body) / 9pt (variables)

14mm


12mm

12mm


10mm

12mm


Code width

10mm


12mm

27mm


25mm

1. NAME OF THE MEDICINAL PRODUCT

Heparin Sodium 10 I.U./ml Flushing Solution for 

maintenance of patency of intravenous devices.

2. QUALITATIVE AND QUANTITATIVE COMPOSITION

Heparin sodium 10 I.U./ml (50 I.U. in 5ml)

For a full list of excipients, see section 6.1.

3. PHARMACEUTICAL FORM

Flushing solution for maintenance of patency of 

intravenous devices

A colourless or straw coloured liquid, free from turbidity, 

and from matter that deposits on standing.

4. CLINICAL INDICATIONS 

4.1 Therapeutic indications

Heparin Sodium 10 I.U./ml Flushing Solution is an 

anticoagulant and acts by potentiating the naturally 

occurring inhibitors of thrombin and factor X (Xa).

Heparin Sodium 10 I.U./ml Flushing Solution is indicated 

in any clinical circumstances in which it is desired to 

maintain the patency of indwelling catheters/cannulae, 

attendant lines or heparin locks.



4.2 Posology and method of administration

Heparin Sodium 10 I.U./ml Flushing Solution is not 

recommended for systemic use.

For cleaning indwelling cannulae.

Material to be used as a cannula flush (5ml; 50 units) 

every four hours or as required. 



4.3 Contraindications

The very rare occurrence of established 

hyper-sensitivity to heparin is the only contraindication 

to Heparin Sodium 10 I.U./ml Flushing Solution.



4.4 Special warnings and precautions for use

Caution should be exercised in patients with known 

hypersensitivity to low molecular weight heparins.

Rigorous aseptic technique should be observed at all 

times in its use.

Platelet counts should be measured in patients 

receiving heparin flushes for longer than five days 

(or earlier in patients with previous exposure to 

heparin). In those who develop thrombocytopenia or 

paradoxical thrombosis, heparin should immediately be 

eliminated from all flushes and ports.

Repeated flushing of a catheter device with heparin 

may result in a systemic anticoagulant effect.

4.5 Interaction with other medicinal products 

      and other forms of interactions

When an indwelling device is used for repeated 

withdrawal of blood samples for laboratory analyses 

and the presence of heparin or saline is likely to 

interfere with or alter results of the desired blood tests, 

the in situ heparin flush solution should be cleared from 

the device by aspirating and discarding a volume of 

solution equivalent to that of the indwelling 

venipuncture device before the desired blood sample 

is taken.



4.6 Use during pregnancy and lactation

The safety of Heparin Sodium 10 I.U./ml Flushing 

Solution in pregnancy is not established, but the dose of 

heparin involved would not be expected to constitute a 

hazard.

Heparin does not appear in breast milk.



4.7 Effects on ability to drive and use machines

None stated. 



4.8 Undesirable effects

Used as directed, it is extremely unlikely that the low 

levels of heparin reaching the blood will have any 

systemic effect. However, there have been rare reports 

of immune-mediated thrombocytopenia and thrombosis 

in patients receiving heparin flushes (see also 

Section 4.4, Special Warnings and Precautions for Use).

Hypersensitivity reactions to heparin are rare.  

They include urticaria, conjunctivitis, rhinitis, asthma, 

cyanosis, tachypnoea, feeling of oppression, fever, 

chills, angioneurotic oedema and anaphylactic shock.

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after 

authorisation of the medicinal product is important. 

It allows continued monitoring of the benefit/risk 

balance of the medicinal product. Healthcare 

professionals are asked to report any suspected 

adverse reactions via the national reporting system:



United Kingdom

Yellow Card Scheme

www.mhra.gov.uk/yellowcard

Ireland

HPRA Pharmacovigilance

Earlsfort Terrace 

IRL - Dublin 2

Tel: +353 1 6764971

Fax: +353 1 6762517

Website: www.hpra.ie

e-mail: medsafety@hpra.ie



Malta

ADR Reporting

www.medicinesauthority.gov.mt/adrportal

4.9 Overdose symptoms

None stated



5 PHARMACOLOGICAL PROPERTIES

5.1 Pharmacodynamic properties

Heparin Sodium 10 I.U./ml Flushing Solution, containing 

only 50 I.U. of sodium heparin per ampoule (5ml), 

is used for flushing indwelling cannulae.  This is unlikely 

to produce blood levels of heparin having any systemic 

effect.


5.2 Pharmacokinetic properties

None stated



5.3 Preclinical safety data

There are no pre-clinical data of relevance to the 

prescriber which are additional to those already 

included in other sections.



6 PHARMACEUTICAL PARTICULARS 

6.1 List of excipients

Sodium chloride 

Water for injections 

Hydrochloric acid 3M

Sodium hydroxide 3M

6.2 Incompatibilities

The following drugs are incompatible with heparin;

Amikacin sulphate, gentamicin sulphate, netilmicin 

sulphate, pethidine hydrochloride, promethazine 

hydrochloride and tobramycin sulphate.

Heparin and reteplase are incompatible when combined 

in solution.

If reteplase and heparin are to be given through the 

same line this, together with any Y-lines, must be 

thoroughly flushed with a 0.9% saline or a 5% glucose 

solution prior to and following the reteplase injection.

6.3 Shelf life

Unopened – 3 years

From a microbiological point of view, unless the method 

of opening precludes the risk of microbial 

contamination, the product should be used immediately.  

If not used immediately, in-use storage times and 

conditions are the responsibility of the user.

6.4 Special precautions for storage

Do not store above 25°C

Store in the original package

6.5 Nature and contents of container

5ml clear glass ampoules. Carton contains 

10 ampoules.

6.6 Special precautions for disposal

Not applicable



7 MARKETING AUTHORISATION HOLDER

Wockhardt UK Ltd 

Ash Road North

Wrexham


LL13 9UF

UK.


8 MARKETING AUTHORISATION NUMBER(S)

PL 29831/0112

PA 1339/10/1

MA 154/01601



9 DATE OF FIRST AUTHORISATION/RENEWAL 

   OF THE AUTHORISATION

Date of first authorisation:

11 September 2007(UK)

16 November 2007 (Republic of Ireland)



10  DATE OF REVISION OF THE TEXT

September 2015



Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist or nurse. 

This includes any possible side effects not listed in this leaflet. You can also 

report side effects directly via the national reporting systems listed below.



United Kingdom

Yellow Card Scheme

www.mhra.gov.uk/yellowcard

Ireland

HPRA Pharmacovigilance

Earlsfort Terrace 

IRL - Dublin 2

Tel: +353 1 6764971

Fax: +353 1 6762517

Website: www.hpra.ie

e-mail:medsafety@hpra.ie



Malta

ADR Reporting

www.medicinesauthority.gov.mt/adrportal

By reporting side effects you can help provide more information on the safety of this medicine.



5. HOW TO STORE HEPARIN SODIUM 10 I.U./ML FLUSHING SOLUTION

Keep this medicine out of the reach and sight of children.

•  The medicine should not be used if the expiry date on the ampoule has passed. 

  The expiry date refers to the last day of the month.

•  Do not use if the contents of the ampoule show signs of deterioration such as discolouration.  

•  This medicine should not be stored above 25ºC.  

•  Store in the original package in order to protect from light.

•  Any portion of the contents not used at once should be discarded.

Medicines should not be disposed of via wastewater or household waste. 

Ask your pharmacist how to dispose of medicines no longer required. These measures will help to 

protect the environment.



6. FURTHER INFORMATION

What Heparin Sodium 10 I.U./ml Flushing Solution contains

Heparin Sodium 10 I.U./ml Flushing Solution is heparinised saline which is heparin dissolved in a 

salt water solution. It is available as a sterile heparinised saline flush solution in one strength of 

10 international units per ml. Each 5ml ampoule contains 50 international units of heparin sodium.

The active ingredient in Heparin Sodium 10 I.U./ml Flushing Solution is heparin sodium. 

Other ingredients are sodium chloride, water for injections, hydrochloric acid and sodium hydroxide.



What Heparin Sodium 10 I.U./ml Flushing Solution looks like and the contents of the pack

Heparin Sodium 10 I.U./ml Flushing Solution is a colourless or straw-coloured liquid. The registered 

pack size is 10 glass ampoules.

X-PIL Information

To listen to or request a copy of this leaflet in Braille, large print or audio please call, free of charge:



0800 198 5000 (UK Only)

Please be ready to give the following information:

           Product Name                          Reference Number

    Heparin Sodium 10 I.U./ml                   29831/0112

           Flushing Solution  

 

             



This is a service provided by the Royal National Institute of  Blind People.

Marketing Authorisation holder and Manufacturer

Marketing Authorisation holder: Wockhardt UK Ltd, Ash Road North, Wrexham, LL13 9UF, UK

Manufacturer: CP Pharmaceuticals Ltd, Ash Road North, Wrexham, LL13 9UF, UK.



This leaflet was last revised in 09/2015

PACKAGE LEAFLET: INFORMATION FOR THE USER

HEPARIN SODIUM 10 I.U./ML FLUSHING SOLUTION  FOR 

MAINTENANCE  OF PATENCY OF INTRAVENOUS DEVICES 

 

Read all of this leaflet carefully before you are given this medicine.

-  Keep this leaflet. You may need to read it again while you are receiving 

  your treatment.

-  If you have any further questions, please ask your doctor or nurse.

-  This medicine has been prescribed for you. It should not be shared 

  with other patients.

The name of your medicine is Heparin Sodium 10 I.U./ml Flushing Solution for 

maintenance of patency of intravenous devices.  In the rest of this leaflet it is 

called Heparin Sodium 10 I.U./ml Flushing Solution.

In this leaflet: 

1. What Heparin Sodium 10 I.U./ml Flushing Solution is and what it is used for

2. Before you use Heparin Sodium 10 I.U./ml Flushing Solution

3. How to use Heparin Sodium 10 I.U./ml Flushing Solution

4. Possible side effects

5. How to store Heparin Sodium 10 I.U./ml Flushing Solution

6. Further information 

1. WHAT HEPARIN SODIUM 10 I.U./ ML FLUSHING SOLUTION IS AND WHAT 

  IT IS USED FOR

Heparin Sodium 10 I.U./ml Flushing Solution is heparinised saline which is heparin dissolved in a 

salt water solution.

Heparin is an anti-clotting agent and is produced naturally in the body. Heparin Sodium 10 I.U./ml 

Flushing Solution is used to wash and rinse the inside of catheters, cannulas and other surgical 

forms of tubing to ensure they do not become blocked while they are in use. 



2. BEFORE YOU USE HEPARIN SODIUM 10 I.U./ ML FLUSHING SOLUTION 

Do not use Heparin Sodium 10 I.U./ Flushing Solution if:

•  you have been told you are allergic to heparin.



Pregnancy and breast-feeding

Do not use Heparin Sodium 10 I.U./ml Flushing Solution if you are pregnant or trying to become 

pregnant without talking to your doctor first.

Do not use Heparin Sodium 10 I.U./ml Flushing Solution if you are breast-feeding without talking to 

your doctor.

If you have any doubts about whether Heparin Sodium 10 I.U./ml Flushing Solution should be used 

for you then discuss things more fully with your doctor or nurse.

3. HOW TO USE HEPARIN SODIUM 10 I.U./ ML FLUSHING SOLUTION 

•  Heparin Sodium 10 I.U./ ml Flushing Solution should not be injected directly into the body. 

•  Heparin Sodium 10 I.U./ml Flushing Solution is used for cleaning catheters, cannulas and other 

  surgical forms of tubing by flushing with 5ml (50 units) every four hours or as required.

•  The doctor will decide which dose is best to be used.

•  If blood for tests are to be taken from the tubing which has been rinsed with this product, 

  the heparin in the tubing should first be withdrawn and discarded.

•  Aseptic techniques should be used at all times during its use to avoid contamination.

•  Your doctor will check your blood if you use Heparin Sodium 10 I.U./ml Flushing Solution 

  for longer than five days.



4. POSSIBLE SIDE EFFECTS

Like many medicines Heparin Sodium 10 I.U./ml Flushing Solution may cause side effects in some 

patients, although not everybody gets them, particularly when treatment is first started. 

•  It can cause bleeding and occasionally a serious blood disorder (thrombocytopenia) which can 

  cause thrombosis (clotting in the blood vessels).  

•  Rarely, allergic reactions can occur.



Measure bar should be 150mm at 100% scale 

Customer


Description

Item Code

Profile

Size


Min. Point Size

Market


Language

Proof By


Proof No.

Date


Artwork No.

Pharma


Code

Colours Used

Wockhardt UK Limited

Heparin Flush Soln 10U/ML Amp

106935-2

n/a


375mm x 148mm

matthew.turrell

1

24/09/2015



597013

322


Process Black

Text free area (non-printing)

Pharmacode Area (non-printing)

Keylines (non printing)

artwork.leicester@multipkg.com

Clearly mark any amendments on one proof and return to MPS

Warning! 

We cannot accept responsibility for any errors 

in this proof after approval. Whilst we take extreme care 

at all times to ensure accuracy to our clientʼs brief,

the final responsibility must be taken by our client. 

IF YOU SIGN THIS PROOF YOU ARE SIGNIFYING

FULL APPROVAL OF DESIGN AND TEXT.

UK

English



8.5pt (main body) / 9pt (variables)

1. NAME OF THE MEDICINAL PRODUCT

Heparin Sodium 10 I.U./ml Flushing Solution for 

maintenance of patency of intravenous devices.

2. QUALITATIVE AND QUANTITATIVE COMPOSITION

Heparin sodium 10 I.U./ml (50 I.U. in 5ml)

For a full list of excipients, see section 6.1.

3. PHARMACEUTICAL FORM

Flushing solution for maintenance of patency of 

intravenous devices

A colourless or straw coloured liquid, free from turbidity, 

and from matter that deposits on standing.

4. CLINICAL INDICATIONS 

4.1 Therapeutic indications

Heparin Sodium 10 I.U./ml Flushing Solution is an 

anticoagulant and acts by potentiating the naturally 

occurring inhibitors of thrombin and factor X (Xa).

Heparin Sodium 10 I.U./ml Flushing Solution is indicated 

in any clinical circumstances in which it is desired to 

maintain the patency of indwelling catheters/cannulae, 

attendant lines or heparin locks.



4.2 Posology and method of administration

Heparin Sodium 10 I.U./ml Flushing Solution is not 

recommended for systemic use.

For cleaning indwelling cannulae.

Material to be used as a cannula flush (5ml; 50 units) 

every four hours or as required. 



4.3 Contraindications

The very rare occurrence of established 

hyper-sensitivity to heparin is the only contraindication 

to Heparin Sodium 10 I.U./ml Flushing Solution.



4.4 Special warnings and precautions for use

Caution should be exercised in patients with known 

hypersensitivity to low molecular weight heparins.

Rigorous aseptic technique should be observed at all 

times in its use.

Platelet counts should be measured in patients 

receiving heparin flushes for longer than five days 

(or earlier in patients with previous exposure to 

heparin). In those who develop thrombocytopenia or 

paradoxical thrombosis, heparin should immediately be 

eliminated from all flushes and ports.

Repeated flushing of a catheter device with heparin 

may result in a systemic anticoagulant effect.

4.5 Interaction with other medicinal products 

      and other forms of interactions

When an indwelling device is used for repeated 

withdrawal of blood samples for laboratory analyses 

and the presence of heparin or saline is likely to 

interfere with or alter results of the desired blood tests, 

the in situ heparin flush solution should be cleared from 

the device by aspirating and discarding a volume of 

solution equivalent to that of the indwelling 

venipuncture device before the desired blood sample 

is taken.



4.6 Use during pregnancy and lactation

The safety of Heparin Sodium 10 I.U./ml Flushing 

Solution in pregnancy is not established, but the dose of 

heparin involved would not be expected to constitute a 

hazard.

Heparin does not appear in breast milk.



4.7 Effects on ability to drive and use machines

None stated. 



4.8 Undesirable effects

Used as directed, it is extremely unlikely that the low 

levels of heparin reaching the blood will have any 

systemic effect. However, there have been rare reports 

of immune-mediated thrombocytopenia and thrombosis 

in patients receiving heparin flushes (see also 

Section 4.4, Special Warnings and Precautions for Use).

Hypersensitivity reactions to heparin are rare.  

They include urticaria, conjunctivitis, rhinitis, asthma, 

cyanosis, tachypnoea, feeling of oppression, fever, 

chills, angioneurotic oedema and anaphylactic shock.

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after 

authorisation of the medicinal product is important. 

It allows continued monitoring of the benefit/risk 

balance of the medicinal product. Healthcare 

professionals are asked to report any suspected 

adverse reactions via the national reporting system:



United Kingdom

Yellow Card Scheme

www.mhra.gov.uk/yellowcard

Ireland

HPRA Pharmacovigilance

Earlsfort Terrace 

IRL - Dublin 2

Tel: +353 1 6764971

Fax: +353 1 6762517

Website: www.hpra.ie

e-mail: medsafety@hpra.ie



Malta

ADR Reporting

www.medicinesauthority.gov.mt/adrportal

4.9 Overdose symptoms

None stated



5 PHARMACOLOGICAL PROPERTIES

5.1 Pharmacodynamic properties

Heparin Sodium 10 I.U./ml Flushing Solution, containing 

only 50 I.U. of sodium heparin per ampoule (5ml), 

is used for flushing indwelling cannulae.  This is unlikely 

to produce blood levels of heparin having any systemic 

effect.


5.2 Pharmacokinetic properties

None stated



5.3 Preclinical safety data

There are no pre-clinical data of relevance to the 

prescriber which are additional to those already 

included in other sections.



6 PHARMACEUTICAL PARTICULARS 

6.1 List of excipients

Sodium chloride 

Water for injections 

Hydrochloric acid 3M

Sodium hydroxide 3M

6.2 Incompatibilities

The following drugs are incompatible with heparin;

Amikacin sulphate, gentamicin sulphate, netilmicin 

sulphate, pethidine hydrochloride, promethazine 

hydrochloride and tobramycin sulphate.

Heparin and reteplase are incompatible when combined 

in solution.

If reteplase and heparin are to be given through the 

same line this, together with any Y-lines, must be 

thoroughly flushed with a 0.9% saline or a 5% glucose 

solution prior to and following the reteplase injection.

6.3 Shelf life

Unopened – 3 years

From a microbiological point of view, unless the method 

of opening precludes the risk of microbial 

contamination, the product should be used immediately.  

If not used immediately, in-use storage times and 

conditions are the responsibility of the user.

6.4 Special precautions for storage

Do not store above 25°C

Store in the original package

6.5 Nature and contents of container

5ml clear glass ampoules. Carton contains 

10 ampoules.

6.6 Special precautions for disposal

Not applicable



7 MARKETING AUTHORISATION HOLDER

Wockhardt UK Ltd 

Ash Road North

Wrexham


LL13 9UF

UK.


8 MARKETING AUTHORISATION NUMBER(S)

PL 29831/0112

PA 1339/10/1

MA 154/01601



9 DATE OF FIRST AUTHORISATION/RENEWAL 

   OF THE AUTHORISATION

Date of first authorisation:

11 September 2007(UK)

16 November 2007 (Republic of Ireland)



10  DATE OF REVISION OF THE TEXT

September 2015



Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist or nurse. 

This includes any possible side effects not listed in this leaflet. You can also 

report side effects directly via the national reporting systems listed below.



United Kingdom

Yellow Card Scheme

www.mhra.gov.uk/yellowcard

Ireland

HPRA Pharmacovigilance

Earlsfort Terrace 

IRL - Dublin 2

Tel: +353 1 6764971

Fax: +353 1 6762517

Website: www.hpra.ie

e-mail:medsafety@hpra.ie



Malta

ADR Reporting

www.medicinesauthority.gov.mt/adrportal

By reporting side effects you can help provide more information on the safety of this medicine.



5. HOW TO STORE HEPARIN SODIUM 10 I.U./ML FLUSHING SOLUTION

Keep this medicine out of the reach and sight of children.

•  The medicine should not be used if the expiry date on the ampoule has passed. 

  The expiry date refers to the last day of the month.

•  Do not use if the contents of the ampoule show signs of deterioration such as discolouration.  

•  This medicine should not be stored above 25ºC.  

•  Store in the original package in order to protect from light.

•  Any portion of the contents not used at once should be discarded.

Medicines should not be disposed of via wastewater or household waste. 

Ask your pharmacist how to dispose of medicines no longer required. These measures will help to 

protect the environment.



6. FURTHER INFORMATION

What Heparin Sodium 10 I.U./ml Flushing Solution contains

Heparin Sodium 10 I.U./ml Flushing Solution is heparinised saline which is heparin dissolved in a 

salt water solution. It is available as a sterile heparinised saline flush solution in one strength of 

10 international units per ml. Each 5ml ampoule contains 50 international units of heparin sodium.

The active ingredient in Heparin Sodium 10 I.U./ml Flushing Solution is heparin sodium. 

Other ingredients are sodium chloride, water for injections, hydrochloric acid and sodium hydroxide.



What Heparin Sodium 10 I.U./ml Flushing Solution looks like and the contents of the pack

Heparin Sodium 10 I.U./ml Flushing Solution is a colourless or straw-coloured liquid. The registered 

pack size is 10 glass ampoules.

X-PIL Information

To listen to or request a copy of this leaflet in Braille, large print or audio please call, free of charge:



0800 198 5000 (UK Only)

Please be ready to give the following information:

           Product Name                          Reference Number

    Heparin Sodium 10 I.U./ml                   29831/0112

           Flushing Solution  

 

             



This is a service provided by the Royal National Institute of  Blind People.

Marketing Authorisation holder and Manufacturer

Marketing Authorisation holder: Wockhardt UK Ltd, Ash Road North, Wrexham, LL13 9UF, UK

Manufacturer: CP Pharmaceuticals Ltd, Ash Road North, Wrexham, LL13 9UF, UK.



This leaflet was last revised in 09/2015

106935/2


106935/2

PACKAGE LEAFLET: INFORMATION FOR THE USER

HEPARIN SODIUM 10 I.U./ML FLUSHING SOLUTION  FOR 

MAINTENANCE  OF PATENCY OF INTRAVENOUS DEVICES 

 

Read all of this leaflet carefully before you are given this medicine.

-  Keep this leaflet. You may need to read it again while you are receiving 

  your treatment.

-  If you have any further questions, please ask your doctor or nurse.

-  This medicine has been prescribed for you. It should not be shared 

  with other patients.

The name of your medicine is Heparin Sodium 10 I.U./ml Flushing Solution for 

maintenance of patency of intravenous devices.  In the rest of this leaflet it is 

called Heparin Sodium 10 I.U./ml Flushing Solution.

In this leaflet: 

1. What Heparin Sodium 10 I.U./ml Flushing Solution is and what it is used for

2. Before you use Heparin Sodium 10 I.U./ml Flushing Solution

3. How to use Heparin Sodium 10 I.U./ml Flushing Solution

4. Possible side effects

5. How to store Heparin Sodium 10 I.U./ml Flushing Solution

6. Further information 

1. WHAT HEPARIN SODIUM 10 I.U./ ML FLUSHING SOLUTION IS AND WHAT 

  IT IS USED FOR

Heparin Sodium 10 I.U./ml Flushing Solution is heparinised saline which is heparin dissolved in a 

salt water solution.

Heparin is an anti-clotting agent and is produced naturally in the body. Heparin Sodium 10 I.U./ml 

Flushing Solution is used to wash and rinse the inside of catheters, cannulas and other surgical 

forms of tubing to ensure they do not become blocked while they are in use. 



2. BEFORE YOU USE HEPARIN SODIUM 10 I.U./ ML FLUSHING SOLUTION 

Do not use Heparin Sodium 10 I.U./ Flushing Solution if:

•  you have been told you are allergic to heparin.



Pregnancy and breast-feeding

Do not use Heparin Sodium 10 I.U./ml Flushing Solution if you are pregnant or trying to become 

pregnant without talking to your doctor first.

Do not use Heparin Sodium 10 I.U./ml Flushing Solution if you are breast-feeding without talking to 

your doctor.

If you have any doubts about whether Heparin Sodium 10 I.U./ml Flushing Solution should be used 

for you then discuss things more fully with your doctor or nurse.

3. HOW TO USE HEPARIN SODIUM 10 I.U./ ML FLUSHING SOLUTION 

•  Heparin Sodium 10 I.U./ ml Flushing Solution should not be injected directly into the body. 

•  Heparin Sodium 10 I.U./ml Flushing Solution is used for cleaning catheters, cannulas and other 

  surgical forms of tubing by flushing with 5ml (50 units) every four hours or as required.

•  The doctor will decide which dose is best to be used.

•  If blood for tests are to be taken from the tubing which has been rinsed with this product, 

  the heparin in the tubing should first be withdrawn and discarded.

•  Aseptic techniques should be used at all times during its use to avoid contamination.

•  Your doctor will check your blood if you use Heparin Sodium 10 I.U./ml Flushing Solution 

  for longer than five days.



4. POSSIBLE SIDE EFFECTS

Like many medicines Heparin Sodium 10 I.U./ml Flushing Solution may cause side effects in some 

patients, although not everybody gets them, particularly when treatment is first started. 

•  It can cause bleeding and occasionally a serious blood disorder (thrombocytopenia) which can 

  cause thrombosis (clotting in the blood vessels).  

•  Rarely, allergic reactions can occur.




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