Population pharmacokinetics and pharmacodynamics of Propofol in morbidly obese patients Jeroen Diepstraten (1), Simone van Kralingen (2), Mariska Y. M. Peeters (1), Eric P. A. van Dongen (2), Bert van Ramshorst (3), Vera H

Population pharmacokinetics and pharmacodynamics of Propofol in morbidly obese patients Jeroen Diepstraten (1), Simone van Kralingen (2), Mariska Y.M. Peeters (1), Eric P.A. van Dongen (2), Bert van Ramshorst (3), Vera H. Deneer (1), Meindert Danhof (4) and Catherijne A.J. Knibbe(1,4) (1) Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands; (2) Department of Anaesthesiology and Intensive Care, St. Antonius Hospital, Nieuwegein, The Netherlands; (3) Department of Surgery, St. Antonius Hospital, Nieuwegein, The Netherlands; (4) Division of Pharmacology, Leiden/ Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands